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Oestrogen acts everywhere in the body, including the parts of the brain that control emotion. Some of oestrogen’s effects include: Increasing serotonin, and the number of serotonin receptors in the brain. Modifying the production and the effects of endorphins, the “feel-good” chemicals in the brain. Only 10% of serotonin is produced in the brain and the rest in the gut. Both are connected by a cable called the vagus nerve. Gut microbiome imbalances may have a direct impact upon your serotonin levels and anxiety due to this connection.

Oestrogen is needed to support the conversion of L tryptophan to serotonin which is why many women in peri-menopause and menopause experience mood disorders and heightened cravings when oestrogen levels decline. Vitamin D, iron, zinc Magnesium and B6 are also essential for the conversion and genetic variations may make this conversion difficult in some.

Nervous System Report

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