Botanical formulations have a long history of traditional use to support and protect the liver. They do so via a number of mechanisms including regeneration of liver cells, enhancing bile production and flow, upregulating detoxification pathways and providing antioxidant support.
The following have been shown in studies to support liver health:
Dandelion (tarax red)
- Source of liver protective polyphenols
- Shown to have antioxidant capabilities by scavenging reactive oxygen species and reactive nitrogen species
- Considered a bitter, which are used to support digestion, in particular where sluggish liver or gallbladder are suspected
Turmeric
- Shown to suppress proinflammatory cytokines and lipid peroxidation products
- Polyphenolic free radical scavenger (antioxidant)
- Shown to support phase 2 pathways
Shizandra
- Studies suggest may reduce liver steatosis and inflammation
Cynara (artichoke)
- Supports antioxidant function, studies showed an increase in superoxide dismutase, catalase, glutathione, and glutathione peroxidase levels (our own anti-oxidants)
- Considered a bitter, which are used to support digestion, in particular where sluggish liver or gallbladder are suspected
Burdock
- Enhances antioxidant enzyme activities and total antioxidant capacity
- May serve as a potential therapeutic compound against both acute inflammation and various chronic diseases
Silymarin (milk thistle)
- High flavonoid content
- Empirical, historical use for liver support
